Indole is a privileged nitrogen heterocycle and is found in structural scaffolds of many biologically active natural products, pharmacologically important agents and organic materials. Among the various indoles, bis(indolyl)methanes (BIMs) are valuable and ubiquitous in numerous natural resources and synthetic compounds. BIMs exhibit a variety of biological properties such as anti-bacterial, anti-oxidative, cytotoxic, anti-tumor, and … Continue reading A simple and efficient preparation of bis(indolyl)methanes catalyzed by HCl/silicagel under solvent-free conditions